| Product Name | ARFGAP2 Antibody (H-120) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | The ADP-ribosylation factor (ARF) protein family are structurally and functionally conserved members of the Ras superfamily of regulatory GTP-binding proteins. ARFs influence vesicle trafficking and signal transduction in eukaryotic cells. ARF-dependent regulatory mechanisms include the coordination of spectrin interactions with Golgi membranes and the association of Actin to the Golgi via Rho family-dependent G-protein localization and WASP/Arp2/3 complexes. Additionally, ARFs play a central role in maintenance of organelle integrity, assembly of coat proteins and activation of phospholipase D (PC-PLD). ZNF289 (zinc finger protein 289), also known as ARFGAP2 (ADP-ribosylation factor GTPase activating protein 2), IRZ, Zfp289 or Nbla10535, functions as a GTPase-activating protein (GAP) for ARF family proteins. Localizing to the cytoplasmic side of the Golgi apparatus, ZNF289 contains one ARF-GAP domain and is found associated with COP-I-coated vesicles. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of ARFGAP2 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including canine | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 311-430 mapping near the C-terminus of ARFGAP2 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 311-430 mapping near the C-terminus of ARFGAP2 of human origin |
| Entrez Gene | 84364 |
|---|
| Application Notes | recommended for detection of ARFGAP2 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including canine |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
