Application
Western blot analysis of truncated human recombinant fractalkine fusion protein.| Product Name | fractalkine Antibody (H-300) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | Chemokines are members of a superfamily of inducible, secreted, pro-inflammatory cytokines. Members of the chemokine family exhibit 20 to 50% homology in their predicted amino acid sequences and are divided into four subfamilies. In the subfamily designated C-C or ∫, the first two cysteines are adjacent. In the C-X-C or å subfamily, the first two of four cysteine residues are separated by a single amino acid. C subfamily members, also designated © chemokines, lack the first and third cysteine residues of the conserved motif. Chemokines in these three subfamilies are small, secreted proteins. Fractalkine, also designated neurotactin, is the first characterized member of a fourth chemokine subfamily. Fractalkine contains a novel C-X3-C motif in which the first two cysteines are separated by three amino acid residues. Fractalkine mRNA has been detected in brain and heart and is upregulated in microglia and endothelial cells by inflammatory signals. The protein exists both as a membrane-bound form and as a chemotactic soluble form. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of fractalkine of human and, to a lesser extent, mouse and rat origin by WB, IP, IF and ELISA | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 98-397 mapping at the C-terminus of fractalkine of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 98-397 mapping at the C-terminus of fractalkine of human origin |
| Entrez Gene | 6376 |
|---|
Application
Western blot analysis of truncated human recombinant fractalkine fusion protein.| Application Notes | recommended for detection of fractalkine of human and, to a lesser extent, mouse and rat origin by WB, IP, IF and ELISA |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
