| Product Name | ARL17 Antibody (H-94) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | ADP-ribosylation factors (ARFs) are highly conserved guanine nucleotide binding proteins that enhance the ADP-ribosyltransferase activity of Cholera Toxin. ARFs are important in eukaryotic vesicular trafficking pathways and they play an essential role in the activation of phospholipase D (PC-PLD). ARL17 (ADP-ribosylation factor-like protein 17), also known as ARF1P2 or ARL17P1, is a 177 amino acid member of the ARF protein family. In human, there are two genes which have been identified as ARL17A and ARL17B that code for identical proteins and colocalize at chromosomal position 17q21.31. ARL17 functions as an activator of the cholera toxin catalytic subunit, an ADP-ribosyltransferase. Localized to the Golgi apparatus, ARL17 may also be involved in the modulation of vesicle budding and uncoating within the Golgi. ARL17 is expressed as three isoforms produced by alternative splicing events. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of ARL17A and ARL17B variants of human origin by WB, IP, IF and ELISA may cross-react with NBR2 (neighbor of BRCA1 gene 2) | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 84-177 mapping at the C-terminus of ARL17 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 84-177 mapping at the C-terminus of ARL17 of human origin |
| Entrez Gene | 641522 |
|---|
| Application Notes | recommended for detection of ARL17A and ARL17B variants of human origin by WB, IP, IF and ELISA may cross-react with NBR2 (neighbor of BRCA1 gene 2) |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
