| Product Name | TDRD7 Antibody (H-105) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | TDRD7 (tudor domain containing 7), also known as TRAP, CATC4 or PCTAIRE2BP, is a 1,098 amino acid cytoplasmic protein that localizes to RNA granules. TDRD7 is present in the chromatoid body (CB) of spermatids and is detected in the intermitochondrial cementin of pachytene spermatocytes. TDRD7 contains three lotus/OST-HTH domains and two tudor domains, and forms a mRNP complex with TDRD1, TDRD6 and VASA. TDRD7 is a component of cytoplasmic RNA granules involved in post-transcriptional regulation of specific genes. Required for lens transparency during lens development, TDRD7 is also required during spermatogenesis. Mutations in the gene encoding TDRD7 leads to cataract congenital autosomal recessive type 4 (CATC4), which is characterized by an opacification of the crystalline lens of the eye. TDRD7 exists as three alternatively spliced isoforms and is encoded by a gene located on human chromosome 9q22.33. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of TDRD7 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including canine, bovine and porcine | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 911-1015 mapping near the C-terminus of TDRD7 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 911-1015 mapping near the C-terminus of TDRD7 of human origin |
| Entrez Gene | 23424 |
|---|
| Application Notes | recommended for detection of TDRD7 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including canine, bovine and porcine |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
