RMND1 (required for meiotic nuclear division protein 1 homolog), also known as C6orf96, is a 449 amino acid protein that belongs to the RMD1/sif2 family. Existing as three alternatively spliced isoforms, the gene encoding RMND1 maps to human chromosome 6q25.1 and mouse chromosome 10 A1. Human chromosome 6 contains 170 million base pairs and comprises nearly 6% of the human genome. Deletion of a portion of the q arm of chromosome 6 is associated with early onset intestinal cancer, suggesting the presence of a cancer susceptibility locus. Additionally, Porphyria cutanea tarda, Parkinson's disease, Stickler syndrome and a susceptibility to bipolar disorder are all associated with genes that map to chromosome 6.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFELISA
recommended for detection of RMND1 of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with RMND5A or RMND5B also reactive with additional species, including equine, canine, bovine and porcine
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
epitope mapping within an internal region of RMND1 of human origin
Tissue Specificity
epitope mapping within an internal region of RMND1 of human origin
Western blot analysis of RMND1 expression in non-transfected: (A) and human RMND1 transfected: (B) 293T whole cell lysates.
Application Notes
recommended for detection of RMND1 of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with RMND5A or RMND5B also reactive with additional species, including equine, canine, bovine and porcine
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.