VCC-1 (VEGF co-regulated chemokine 1), also known as Dcip1, DMC (dendritic cell and monocyte chemokine-like protein) or CXCL17 (C-X-C motif chemokine 17), is a 119 amino acid secreted protein that plays a role in angiogenesis. A member of the intercrine alpha (chemokine CxC) family, VCC-1 is expressed in skeletal muscle, trachea, lung, intestine and stomach, and is upregulated in duodenal mucosa of patients with acute cholera, as well as breast tumors. VCC-1 is considered a housekeeping chemokine for the movement of immature dendritic cells and non activated blood monocytes into tissues, and is though to be involved in the innate immune response. The gene encoding VCC-1 maps to human chromosome 19q13.2 and mouse chromosome 7 A3.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFELISA
recommended for detection of VCC-1 of mouse and rat origin by WB, IP, IF and ELISA
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
epitope corresponding to amino acids 70-119 mapping at the C-terminus of VCC-1 of mouse origin
Tissue Specificity
epitope corresponding to amino acids 70-119 mapping at the C-terminus of VCC-1 of mouse origin