| Product Name | SEMA4F Antibody (H-138) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 90-227 mapping within an internal region of SEMA4F of human origin |
| Modification Notes | Semaphorins are a family of cell surface and secreted proteins that are conserved from insects to humans. Members of this family of proteins are approximately 750 amino acids in length (including signal sequences) and are defined by a conserved extracellular “semaphorin” domain of approximately 500 amino acids containing 14-16 cysteines, blocks of conserved sequences and no obvious repeats. Secreted and cell-bound semaphorins chemically attract and repel the growth of neural axons, guiding the development of intricate networks of neural tissue. SEMA4F (semaphorin-4F), also known as SEMAM, SEMAW or PRO2353, is a 770 amino acid member of the semaphorin family. Localized to the membrane, SEMA4F is a single-pass type I protein that is involved in growth cone collapse of retinal ganglion-cell axons. SEMA4F is highly expressed in postnatal brain and lung and contains one immunogloblin-like (Ig-like) domain, one PSI domain and one semaphorin domain. Two isoforms exist due to alternative splicing events. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of Semaphorin-4F of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine and porcine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 90-227 mapping within an internal region of SEMA4F of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 90-227 mapping within an internal region of SEMA4F of human origin |
| Entrez Gene | 10505 |
|---|
| Application Notes | recommended for detection of Semaphorin-4F of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine and porcine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
