| Product Name | BANP Antibody (H-129) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 211-339 mapping within an internal region of BANP of human origin |
| Modification Notes | BANP (BTG3 associated nuclear protein), also known as BEND1, SMARBP1 or SMAR1, is a 519 amino acid protein that localizes to the nucleus and belongs to the BANP/SMAR1 family. Interacting with CDP and p53, BANP functions to control V(D)J recombination during T-cell development, specifically by binding to a scaffold/matrix DNA attachment region and repressing the enhancer function of TCR∫ (T-cell receptor beta). Additionally, BANP promotes p53 serine phosphorylation, resulting in the subsequent nuclear accumulation of p53 and, ultimately, cell cycle arrest. BANP is down regulated in breast cancer cells, suggesting a role in tumor suppression. Three isoforms of BANP exist due to alternative splicing events. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of BANP of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine, porcine and avian: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 211-339 mapping within an internal region of BANP of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 211-339 mapping within an internal region of BANP of human origin |
| Entrez Gene | 54971 |
|---|
| Application Notes | recommended for detection of BANP of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine, porcine and avian: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
