| Product Name | LCE3B-E Antibody (C-14) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope mapping near the C-terminus of LCE3D of human origin |
| Modification Notes | The lipid-corneocyte structure of stratum corneum is responsible for barrier activity of skin and internal barrier-forming epithelial linings. Corneocyte stability is dependent upon the outer cornified envelope and is essential for maintenance of barrier function. Within the epidermal differentiation complex on human chromosome 1 and mouse chromosome 3 lies the late cornified envelope (LCE) gene cluster, which contains multiple conserved genes encoding stratum-corneum proteins. Late cornified envelope proteins 3B, 3C, 3D and 3E (LCE3B, C, D and E) are a group of proteins that contain between 92-95 amino acids each and are precursors of the cornified envelope of the stratum corneum. All four proteins are expressed specifically in skin and are encoded by genes that map to the LCE gene cluster present on chromosome 1q21. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIFELISA |
| recommended for detection of LCE3B, LCE3C, LCE3D and LCE3E of human origin by WB, IF and ELISA may cross-react with LCE3A: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping near the C-terminus of LCE3D of human origin |
|---|---|
| Tissue Specificity | epitope mapping near the C-terminus of LCE3D of human origin |
| Entrez Gene | 84648 |
|---|
| Application Notes | recommended for detection of LCE3B, LCE3C, LCE3D and LCE3E of human origin by WB, IF and ELISA may cross-react with LCE3A: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
