| Product Name | FHOD3 Antibody (M-102) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 1-102 mapping at the N-terminus of FHOD3 of mouse origin |
| Modification Notes | FHOD3 (formin homology 2 domain containing 3), also known as FHOS2 or KIAA1695, is a 1,422 amino acid protein that localizes to both the cytoplasm and the cytoskeleton and contains one DAD domain, one FH1 domain, one FH2 domain and one GBD/FH3 domain. Expressed in brain, heart and kidney, FHOD3 interacts with intermediate filaments and functions as an Actin-organizing protein that is thought to promote the formation of stress fibers in conjunction with cellular elongation. Multiple isoforms of FHOD3 exist due to alternative splicing events. The gene encoding FHOD3 maps to human chromosome 18, which houses over 300 protein-coding genes and contains nearly 76 million bases. There are a variety of diseases associated with defects in chromosome 18-localized genes, some of which include Trisomy 18 (also known as Edwards syndrome), Niemann-Pick disease, hereditary hemorrhagic telangiectasia, erythropoietic protoporphyria and follicular lymphomas. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of FHOD3 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including canine and bovine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 1-102 mapping at the N-terminus of FHOD3 of mouse origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 1-102 mapping at the N-terminus of FHOD3 of mouse origin |
| Entrez Gene | 80206 |
|---|
| Application Notes | recommended for detection of FHOD3 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including canine and bovine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
