epitope mapping within an internal region of RIMKLB of human origin
Modification Notes
RIMKLB (ribosomal modification protein rimK-like family member B), also known as NAAGS (N-acetyl-aspartyl-glutamate synthetase B), beta-citryl-glutamate synthase B or FAM80B, is a 386 amino acid cytoplasmic protein that belongs to the rimK family. Acting as the catalyst in the synthesis of beta-citryl-glutamate and N-acetyl-aspartyl-glutamate, RIMKLB contains one ATP-grasp domain and exists as two alternatively spliced isoforms. The gene encoding RIMKLB maps to human chromosome 12, which encodes over 1,100 genes and comprises approximately 4.5% of the human genome. Chromosome 12 is associated with a variety of diseases and afflictions, including hypochondrogenesis, achondrogenesis, Kniest dysplasia, Noonan syndrome and trisomy 12p, which causes facial developmental defects and seizure disorders.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFELISA
recommended for detection of RIMKLB of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with FAM80A also reactive with additional species, including equine, canine, bovine, porcine and avian:
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
epitope mapping within an internal region of RIMKLB of human origin
Tissue Specificity
epitope mapping within an internal region of RIMKLB of human origin
Western blot analysis of RIMKLB expression in non-transfected: (A) and human RIMKLB transfected: (B) 293T whole cell lysates.
Application Notes
recommended for detection of RIMKLB of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with FAM80A also reactive with additional species, including equine, canine, bovine, porcine and avian:
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.