| Product Name | ATP6L Antibody (H-127) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | ATP6L, also known as ATP6V0C, Vma3, ATPL, VATL or ATP6C, is a vacuolar-type H+-ATPase (V-ATPase). V-ATPases are multisubunit enzymes responsible for acidification of eukaryotic intracellular organelles. V-ATPases pump protons against an electrochemical gradient, while F-ATPases reverse the process, thereby synthesizing ATP. A peripheral V1 domain, which is responsible for ATP hydrolysis, and an integral V0 domain, which is responsible for proton translocation, compose V-ATPase. Nine subunits (A-H) make up the V1 domain and five subunits (a, d, c, c' and c") make up the V0 domain. Consisting or 155 amino acids, ATP6L is a multi-pass membrane protein that makes up part of the V0 domain. The gene encoding ATP6L maps to human chromosome 16p13.3 and mouse chromosome 17 A3.3. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of ATP6L of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine, porcine and avian | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 29-155 mapping at the C-terminus of ATP6L of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 29-155 mapping at the C-terminus of ATP6L of human origin |
| Application Notes | recommended for detection of ATP6L of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine, porcine and avian |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
