| Modification Notes |
Follicle-stimulating hormone (FSH), also called follitropin, belongs to the family of glycoprotein hormones that also includes luteininizing hormone and thyroid-stimulating hormone. These hormones are secreted by the pituitary and exist as heterodimers, consisting of a common å subunit and a homologous but distinct ∫ subunit. While the å subunit of FSH is involved in the binding of FSH to the receptor (follicle-stimulating hormone receptor, also known as FSHR), the ∫ subunit stabilizes this interaction. This heterodimer regulates a variety of processes, including secretion, posttranslational modification and signal transduction. Both FSH and FSHR are localized to Sertoli cells. |