| Product Name | TRIM48 Antibody (D-14) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | The tripartite motif (TRIM) family of proteins are characterized by a conserved TRIM domain that includes a coiled-coil region, a B-box type zinc finger, one RING finger and three zinc-binding domains. Many TRIM proteins are induced by type I and type II interferons, making them crucial for development of pathogen-resistance. TRIM48 (Tripartite motif-containing protein 48), also known as RING finger protein 101, is a 208 amino acid protein that contains one RING-type zinc finger and one B box-type zinc finger. The gene encoding TRIM48 maps to human chromosome 11, which houses over 1,400 genes and comprises nearly 4% of the human genome. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are associated with defects in genes that maps to chromosome 11. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIFELISA |
| recommended for detection of TRIM48 of human origin by WB, IF and ELISA non cross-reactive with other TRIM family members | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping within an internal region of TRIM48 of human origin |
|---|---|
| Tissue Specificity | epitope mapping within an internal region of TRIM48 of human origin |
| Entrez Gene | 79097 |
|---|
| Application Notes | recommended for detection of TRIM48 of human origin by WB, IF and ELISA non cross-reactive with other TRIM family members |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
