LRWD1 (leucine-rich repeats and WD repeat domain containing 1) is a 647 amino acid protein that contains five WD domains and three LRR (leucine-rich) repeats. LRWD1 undergoes post-translational phosphorylation, most likely by ATR or ATM, and is encoded by a gene that maps to human chromosome 7. Human chromosome 7 is about 158 milllion bases long, encodes over 1000 genes and makes up about 5% of the human genome. Chromosome 7 has been linked to Osteogenesis imperfecta, Pendred syndrome, Lissencephaly, Citrullinemia and Shwachman-Diamond syndrome. The deletion of a portion of the q arm of chromosome 7 is associated with Williams-Beuren syndrome, a condition characterized by mild mental retardation, an unusual comfort and friendliness with strangers and an elfin appearance.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFELISA
recommended for detection of LRWD1 of mouse, rat and human origin by WB, IP, IF and ELISA
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
epitope mapping within an internal region of LRWD1 of human origin
Tissue Specificity
epitope mapping within an internal region of LRWD1 of human origin