| Product Name | ABCA3 Antibody (H-120) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 1261-1380 mapping within an internal region of ABCA3 of human origin |
| Modification Notes | The ATP binding cassette (ABC) transporters, or traffic ATPases, constitute an expansive family of proteins accountable for the transport of a wide variety of substrates across cell membranes in both prokaryotic and eukaryotic cells and are involved in the regulation of lipid transport and membrane trafficking. ABCA3 (ATP-binding cassette 3), also designated ATP-binding cassette transporter 3 and ABC transporter 3, has typical structural features of the ABC transporter family and consists of a 1,704 amino acid polypeptide with two homologous repeats, each consisting of six putative transmembrane helices and an ATP-binding cassette motif. ABCA3, the gene encoding the human ABCA3 protein, maps near the polycystic kidney disease type 1 (PKD1) gene on chromosome 16p13.3. The ABCA3 gene is expressed at highest levels in lung. Biochemical and molecular research indicates that ABCA3 is targeted to vesicle membranes and located in the limiting membrane of lamellar bodies and may play a key role in lipid organization during the formation of lamellar bodies. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of ABCA3 of mouse, rat and human origin by WB, IP, IF and ELISA: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 1261-1380 mapping within an internal region of ABCA3 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 1261-1380 mapping within an internal region of ABCA3 of human origin |
| Application Notes | recommended for detection of ABCA3 of mouse, rat and human origin by WB, IP, IF and ELISA: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
