| Product Name | ZDHHC8 Antibody (G-18) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope mapping within an internal region of ZDHHC8 of human origin |
| Modification Notes | Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. ZDHHC8 (zinc finger, DHHC-type containing 8), also known as KIAA1292, ZDHHCL1 or ZNF378 (zinc finger protein 378), is a 765 amino acid multi-pass membrane protein that localizes to the membrane of cytoplasmic vesicles and contains one DHHC-type zinc finger. Expressed as multiple alternatively spliced isoforms, ZDHHC8 functions as a putative palmitoyltransferase that catalyzes the conversion of palmitoyl-CoA and a protein-cysteine to an S-palmitoyl protein and free CoA, a reaction that is important in glutamatergic transmission. Defects in the gene encoding ZDHHC8 may be associated with an increased susceptibility to schizophrenia. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIFELISA |
| recommended for detection of ZDHHC8 of mouse, rat and human origin by WB, IF and ELISA non cross-reactive with other ZDHHC family members also reactive with additional species, including equine, canine and porcine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping within an internal region of ZDHHC8 of human origin |
|---|---|
| Tissue Specificity | epitope mapping within an internal region of ZDHHC8 of human origin |
| Entrez Gene | 29801 |
|---|
| Application Notes | recommended for detection of ZDHHC8 of mouse, rat and human origin by WB, IF and ELISA non cross-reactive with other ZDHHC family members also reactive with additional species, including equine, canine and porcine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
