Application
Western blot analysis of DGS8 expression in HeLa (A) and Jurkat (B) whole cell lysates.Application
Western blot analysis of DGS8 expression in non-transfected: (A) and human DGS8 transfected: (B) 293T whole cell lysates.Application
Western blot analysis of DGS8 expression in non-transfected: (A) and human DGS8 transfected: (B) 293T whole cell lysates.| Product Name | DGS8 Antibody (H-300) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | DGS8, also designated DiGeorge syndrome critical region 8 protein, plays a role in the etiology of the velocardiofacial/DiGeorge syndrome (VCFS/DGS). It is a ubiquitously expressed protein encoded by the gene DGCR8, which is deleted in DiGeorge syndrome. DiGeorge syndrome is characterized by structural and functional palate anomalies, conotruncal cardiac malformations, immunodeficiency, hypocalcemia, and typical facial anomalies. In mouse, DGS8 is detected primarily in embryonic brain, vessels, thymus and palate. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of DGS8 isoforms 1, 2 and 3 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 1-300 mapping at the N-terminus of DGS8 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 1-300 mapping at the N-terminus of DGS8 of human origin |
Application
Western blot analysis of DGS8 expression in HeLa (A) and Jurkat (B) whole cell lysates.
Application
Western blot analysis of DGS8 expression in non-transfected: (A) and human DGS8 transfected: (B) 293T whole cell lysates.
Application
Western blot analysis of DGS8 expression in non-transfected: (A) and human DGS8 transfected: (B) 293T whole cell lysates.| Application Notes | recommended for detection of DGS8 isoforms 1, 2 and 3 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
