Application
Western blot analysis of SDF-2L1 expression in HeLa (A), K-562 (B) and Hep G2 (C) whole cell lysates.| Product Name | SDF2L1 Antibody (C-12) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | SDF-2L1 (stromal cell-derived factor 2-like 1), also known as PWP1-interacting protein 8, is a 221 amino acid protein that localizes to the lumen of the endoplasmic reticulum (ER) and contains three MIR domains. Expressed ubiquitously with highest expression in testis and moderate expression in colon, spleen, pancreas, prostate and small intestine, SDF-2L1 is thought to play a role in the unfolded protein response within the ER and may be involved in the pathogenesis of hepatocellular carcinoma. The gene encoding SDF-2L1 maps to human chromosome 22, which houses over 500 genes and is the second smallest human chromosome. Mutations in several of the genes that map to chromosome 22 are involved in the development of Phelan-McDermid syndrome, Neurofibromatosis type 2, autism and schizophrenia. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of SDF-2L1 of human origin by WB, IP, IF and ELISA also reactive with additional species, including equine and canine | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping at the C-terminus of SDF-2L1 of human origin |
|---|---|
| Tissue Specificity | epitope mapping at the C-terminus of SDF-2L1 of human origin |
| Entrez Gene | 23753 |
|---|
Application
Western blot analysis of SDF-2L1 expression in HeLa (A), K-562 (B) and Hep G2 (C) whole cell lysates.| Application Notes | recommended for detection of SDF-2L1 of human origin by WB, IP, IF and ELISA also reactive with additional species, including equine and canine |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
