Application
Western blot analysis of STOML3 expression in non-transfected 293T: (A), human STOML3 transfected 293T: (B), ES-2 (C), HeLa (D) and Jurkat (E) whole cell lysates.Application
Western blot analysis of STOML3 expression in WI 38 (A), ES-2 (B) and HeLa (C) whole cell lysates.| Product Name | STOML3 Antibody (C-15) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | STOML3 [Stomatin (EPB72)-like 3], whose alternative names include Stomatin-like protein 3, Stomatin-related olfactory protein, SRO, SLP3, Epb7.2l, erythrocyte band 7 integral membrane protein or protein 7.2B, is a 291 amino acid single-pass type III membrane protein belonging to the band 7/mec-2 family. STOML3 is expressed in olfactory sensory neurons, with high expression in apical dendrites. STOML3 is also known to associate with A cyclase III and caveolin-1 in olfactory cilia. STOML3 is essential for regulating odorant signals in olfactory cilia lipid rafts and plays a role in mammalian mechanotransduction. Studies indicate that many ion channels of sensory neurons which depend on mechanical stimuli cannot function in the absence of STOML3. STOML3 contains two N-terminal hydrophobic domains and forms regions rich in beta sheets and alpha helices, which are common to members of the Stomatin family. The gene encoding STOML3 maps to human chromosome 13q13.3. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of STOML3 of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with STOML2 also reactive with additional species, including equine, canine and porcine | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping near the C-terminus of STOML3 of human origin |
|---|---|
| Tissue Specificity | epitope mapping near the C-terminus of STOML3 of human origin |
| Entrez Gene | 161003 |
|---|
Application
Western blot analysis of STOML3 expression in non-transfected 293T: (A), human STOML3 transfected 293T: (B), ES-2 (C), HeLa (D) and Jurkat (E) whole cell lysates.
Application
Western blot analysis of STOML3 expression in WI 38 (A), ES-2 (B) and HeLa (C) whole cell lysates.| Application Notes | recommended for detection of STOML3 of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with STOML2 also reactive with additional species, including equine, canine and porcine |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
