| Product Name | PIG-N Antibody (L-20) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | Several cell surface proteins are attached to the membrane through their C-terminal domain and a glycosylphosphatidylinositol (GPI) moiety. Phosphatidylinositol-glycans (PIGs) are multi-pass transmembrane proteins that localize to the endoplasmic reticulum. PIGs are crucial for the synthesis of N-acetylglucosaminyl-phosphatidylinositol, a very early intermediate in GPI-anchor biosynthesis. PIGs play a role in the recognition of either the GPI attachment signal or the lipid portion of GPI. PIG-N (Phosphatidylinositol-glycan biosynthesis class N protein), also known as GPI ethanolamine phosphate transferase 1 and MCD4 homolog, is a 931 amino acid enzyme of the endoplasmic reticulum that transfers ethanolamine phosphate to the first å-1,4-linked mannose of the glycosylphosphatidylinositol precursor of GPI-anchor. The gene encoding PIG-N is localized near a region of human chromosome 18 that may be implicated in chronic recurrent multifocal osteomyelitis. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIFELISA |
| recommended for detection of PIG-N of mouse, rat and human origin by WB, IF and ELISA non cross-reactive with other PIG family members also reactive with additional species, including equine, canine, bovine and porcine | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping within an internal region of PIG-N of human origin |
|---|---|
| Tissue Specificity | epitope mapping within an internal region of PIG-N of human origin |
| Entrez Gene | 23556 |
|---|
| Application Notes | recommended for detection of PIG-N of mouse, rat and human origin by WB, IF and ELISA non cross-reactive with other PIG family members also reactive with additional species, including equine, canine, bovine and porcine |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
