Members of the glutathione S-transferase (GST) family of proteins function in the detoxification of xenobiotics to protect cells against toxicant-induced damage. There are eight families of GST proteins, namely alpha, zeta, theta, kappa, mu, pi, sigma and omega, each of which are composed of proteins that have a variety of functions throughout the cell. The GSTM proteins (GSTM1-GSTM5 in human and GSTM1-GSTM7 in mouse) are members of the mu class of enzymes that conjugate with glutathione and function in the detoxification of carcinogens, environmental toxins and products of oxidative stress. GSTM3 is a 225 amino acid protein that is expressed in the testis and brain. Localized to the cytoplasm, GSTM3 exists as a homodimer.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFELISA
recommended for detection of GSTM1, GSTM2, GSTM3, GSTM4 and GSTM5 of mouse, rat and human origin and Gstm6 and Gstm7 of mouse and rat origin by WB, IP, IF and ELISA
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
epitope corresponding to amino acids 1-218 representing full length GSTM2 of human origin
Tissue Specificity
epitope corresponding to amino acids 1-218 representing full length GSTM2 of human origin
Western blot analysis of GSTM expression in A-673 whole cell lysate.
Application Notes
recommended for detection of GSTM1, GSTM2, GSTM3, GSTM4 and GSTM5 of mouse, rat and human origin and Gstm6 and Gstm7 of mouse and rat origin by WB, IP, IF and ELISA
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.