| Product Name | PADI4 Antibody (H-70) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | The protein arginine deiminase (PAD) family of proteins are often referred to as peptidylarginine deiminases. They catalyze the deimination of arginine residues of proteins. In the presence of calcium, the proteins in the PAD family act as catalysts for the posttranslational modification reaction that converts methylarginine to citrulline. The PAD proteins are cytoplasmic proteins primarily detected in eosinophils and neutrophils. The gene encoding for PADI4 is believed to be a rheumatoid arthritis susceptibility locus. By increasing the citrullination of proteins in rheumatoid arthritis synovial tissues, it may play a role in the pathogenesis of the disease. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of PADI4 of human origin by WB, IP, IF and ELISA | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 181-250 mapping within an internal region of PADI4 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 181-250 mapping within an internal region of PADI4 of human origin |
| Entrez Gene | 23569 |
|---|
| Application Notes | recommended for detection of PADI4 of human origin by WB, IP, IF and ELISA |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
