| Product Name | ZNF133 Antibody (P-19) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope mapping within an internal region of ZNF133 of human origin |
| Modification Notes | Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. The majority of zinc-finger proteins contain a Krüppel-type DNA binding domain and a KRAB domain, which is thought to interact with KAP1, thereby recruiting histone modifying proteins. ZNF133 (Zinc finger protein 133), also known as ZNF150 (Zinc finger protein 150), is a 654 amino acid transcriptional regulator that is expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. The KRAB domain derived from ZNF133 is suggested to be a potent transcriptional repression domain and its repression activity may be enhanced by PIAS 1 (Protein inhibitor of activated STAT protein 1). |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIFELISA |
| recommended for detection of ZNF133 of human origin by WB, IF and ELISA non cross-reactive with other ZNF family members also reactive with additional species, including equine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping within an internal region of ZNF133 of human origin |
|---|---|
| Tissue Specificity | epitope mapping within an internal region of ZNF133 of human origin |
| Entrez Gene | 7692 |
|---|
| Application Notes | recommended for detection of ZNF133 of human origin by WB, IF and ELISA non cross-reactive with other ZNF family members also reactive with additional species, including equine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
