TNF cytokine family member TALL-1 (also designated BAFF, zTNF4, THANK and BLYS) is a type II membrane protein that shares characteristics with other members of the tumor necrosis factor (TNF) cytokine family. TALL-1 has the ability to bind to three receptors, TACI, BCMA and BAFF-R, but unlike other TNF receptors, BAFF-R specifically binds only the TALL-1 ligand. The gene encoding human BAFF-R, which maps to chromosome 22q13.1-q13.31, is expressed at high levels in spleen and lymph nodes and at lower levels in peripheral blood leukocytes and thymus. Expression of BAFF-R is crucial for selecting transitional B cells into the mature B cell pool.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFELISA
recommended for detection of BAFF-R of human origin by WB, IP, IF and ELISA
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
epitope corresponding to amino acids 22-184 of BAFF-R of human origin
Tissue Specificity
epitope corresponding to amino acids 22-184 of BAFF-R of human origin