Potassium (K+) channels are very widely distributed ion channels that function in regulating charged gradients across cell membranes which are important for resting potential generation, hormonal release and water retention. Potassium channels contain four protein subunits surrounding a central ion conducting pore. The protein subunits can be homotetrameric, producing a symmetric C4 complex, or heterotetrameric, producing a pseudo-symmetric complex. TASK-5 (potassium channel subfamily K member 15), also known as KCNK15, is a potential potassium channel subunit that is thought to form a heterodimer to complete the functional potassium channel. TASK-5 is a membrane bound 330 amino acid polypeptide found at abundant levels in pancreas, heart, placenta, lung, liver, kidney, ovary, testis, skeletal muscle and adrenal gland. TASK-5A, TASK-5B, and TASK-5C are the three known variants of TASK-5 at the protein level.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFELISA
recommended for detection of TASK-5 of human origin by WB, IP, IF and ELISA non cross-reactive with TASK-1, TASK-2, and TASK-3.
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
epitope mapping within a cytoplasmic domain of TASK-5 of human origin
Tissue Specificity
epitope mapping within a cytoplasmic domain of TASK-5 of human origin