| Product Name | C4ST-1 Antibody (H-60) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs and xenobiotic compounds. These cytosolic enzymes differ in their tissue distributions and substrate specificities, although the gene structure (number and length of exons) is similar among family members. Sulfotransferases are primarily expressed in liver and adrenal tissues where they add sulfate to steroids and bile acids. C4ST-1 (chondroitin 4-sulphotransferase-1) transfers sulfate from PAPS (adenosine 3'-phosphate 5'-phosphosulphate) to position 4-O of N-acetylgalactosamine in chondroitin. This sulfation is required for proper chondroitin sulfate localization, modulation of distinct signaling pathways and cartilage growth plate morphogenesis. N-linked oligosaccharides attached to C4ST-1 contribute to the production and stability of the active form of C4ST-1. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of C4ST-1 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and avian | |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 61-120 mapping near the N-terminus of C4ST-1 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 61-120 mapping near the N-terminus of C4ST-1 of human origin |
| Entrez Gene | 50515 |
|---|
| Application Notes | recommended for detection of C4ST-1 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and avian |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
