Immunoperoxidase staining of formalin fixed, paraffin-embedded human heart muscle tissue showing cytoplasmic and inter-calated disc staining of myocytes.
epitope corresponding to amino acids 174-282 mapping within a C-terminal extracellular domain of Tenomodulin of human origin
Modification Notes
Tenomodulin (TEM), also designated chondromodulin-I-like protein (CHM-1L), myodulin or tendin, acts as an angiogenesis inhibitor. It is a single-pass type II membrane protein that belongs to the chondromodulin family of proteins. The deduced 317 amino acid protein contains an N-terminal transmembrane domain and a putative antiangiogenic domain comprised of eight cysteines. Human Tenomodulin shares 96% amino acid identity with mouse Tenomodulin, and it shares 65% identity in a 65-amino acid C-terminal stretch with chondromodulin I. Tenomodulin is expressed in skeletal muscle, eye, whole rib and dense connective tissues, such as epimysium and tendon.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFELISA
recommended for detection of Tenomodulin of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine:
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
epitope corresponding to amino acids 174-282 mapping within a C-terminal extracellular domain of Tenomodulin of human origin
Tissue Specificity
epitope corresponding to amino acids 174-282 mapping within a C-terminal extracellular domain of Tenomodulin of human origin
Immunoperoxidase staining of formalin fixed, paraffin-embedded human heart muscle tissue showing cytoplasmic and inter-calated disc staining of myocytes.
Application Notes
recommended for detection of Tenomodulin of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine:
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.