In E. coli, Era is a GTPase that is crucial for cell cycle progression and proper cell division, playing a key role in cellular proliferation. ERAL1 (Era G-protein-like 1), also known as ERA, ERAL1A, HERA-A, HERA-B or CEGA (conserved ERA-like GTPase), is a 437 amino acid human homolog of Era. Functioning as a probable GTP-binding protein, ERAL1 contains the same structural domains as its yeast counterpart, namely a conserved BoxA sequence, a C-terminal KH domain and an N-terminal GTP-binding domain. Due to the high level of structural similarity with Era, ERAL1 may participate in cell cycle events, including cellular proliferation and cell division. ERAL1 contains one KH type-2 domain and is expressed as two isoforms, designated HERA-A and HERA-B, which are produced due to alternative splicing events.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPELISA
recommended for detection of ERAL1 of human origin by WB, IP and ELISA: