Application
Immunoperoxidase staining of formalin fixed, paraffin-embedded human cancer tissue showing cytoplasmic staining.| Product Name | p-RPTPα Antibody (Ser 180) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | Receptor protein-tyrosine phosphatase å (RPTPå) dephosphorylates and activates Src family tyrosine kinases and influences the regulation of integrin signaling, cell adhesion and growth factor responsiveness. RPTPå contains an extracellular domain, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and constitutively forms dimers in the membrane. The human RPTPa sequence encodes a 793 amino acid protein. Mouse RPTPå precipitated from NIH/3T3 cells is constitutively phosphorylated at Ser180/Ser204. Human RPTPå is subject to phosphorylation on specific amino acid residues, including Ser 180. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | IFIHCELISA |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | recommended for detection of Ser 180 phosphorylated RPTP&alpha of human origin by IF IHC(P) and ELISA |
|---|---|
| Tissue Specificity | recommended for detection of Ser 180 phosphorylated RPTPα of human origin by IF, IHC(P) and ELISA |
| Entrez Gene | 5786 |
|---|
Application
Immunoperoxidase staining of formalin fixed, paraffin-embedded human cancer tissue showing cytoplasmic staining.| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
