| Product Name | NNT Antibody (H-300) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 787-1086 mapping at the C-terminus of NNT of human origin |
| Modification Notes | The proccess of cellular respiration is carried out by integral inner mitochondrial membrane proteins that facilitate the harnessing of energy released by the oxidation of NADH. NNT (Nicotinamide nucleotide transhydrogenase), also known as mitochondrial NAD(P) transhydrogenase or pyridine nucleotide transhydrogenase, is a 1086 amino acid multi-pass mitochondrial inner membrane protein. NNT is a homodimer with an N-terminal section belonging to the AlaDH/PNT family and a C-terminal section belonging to the PNT beta subunit family. NNT catalyzes the transfer of a hydride ion from NADH to NADP+ and functions as a mitochondrial inner membrane proton pump. Using the energy of the proton gradient created by the electron transport chain, NNT produces high concentrations of NADPH, which is used in free radical detoxification and biosynthesis. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of NNT of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 787-1086 mapping at the C-terminus of NNT of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 787-1086 mapping at the C-terminus of NNT of human origin |
| Entrez Gene | 23530 |
|---|
| Application Notes | recommended for detection of NNT of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
