| Product Name | TBC1D12/14 Antibody (H-58) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 571-622 mapping near the C-terminus of TBC1D12 of human origin |
| Modification Notes | GTPase-activating proteins (GAPs) accelerate the intrinsic rate of GTP hydrolysis of Ras-related proteins, resulting in downregulation of their active form. TBC1D12 (TBC1 domain family, member 12) and TBC1D14 (TBC1 domain family, member 14) are 775 and 693 amino acid proteins, respectively, which both contain one Rab-GAP TBC domain and are thought to function as GTPase-activating proteins for Rab family members. The genes encoding TBC1D12 and TBC1D14 map to human chromosomes 10 and 4, respectively. Chromosome 4 encodes nearly 6% of the human genome and has the largest gene deserts (regions of the genome with no protein encoding genes) of all of the human chromosomes, while chromosome 10 houses over 1,200 genes and comprises nearly 4.5% of the human genome. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of TBC1D12 and TBC1D14 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine, porcine and avian: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 571-622 mapping near the C-terminus of TBC1D12 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 571-622 mapping near the C-terminus of TBC1D12 of human origin |
| Application Notes | recommended for detection of TBC1D12 and TBC1D14 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine, porcine and avian: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
