epitope corresponding to amino acids 1-96 representing full length LSm8 of human origin
Modification Notes
Sm and Sm-like (LSm) proteins form donut-shaped heptameric complexes that are involved in various steps of RNA metabolism. LSm proteins are ubiquitously expressed and facilitate RNA-protein interactions and structural changes that are required during ribosomal subunit assembly. LSm8, also known as YJR022W, is a member of the snRNP Sm proteins family. It is a component of the LSm2-8 complex which plays a role in the processing of pre-snoRNAs, pre-tRNAs and pre-rRNAs, as well as the turnover of pre-mRNAs. The LSm2-8 complex is also essential for the nuclear localization of the U6 snRNA. LSm8 localizes to the nucleus and specifically binds the U6 snRNA 3’-terminal U-tract.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFELISA
recommended for detection of LSm8 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine, porcine and avian:
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
epitope corresponding to amino acids 1-96 representing full length LSm8 of human origin
Tissue Specificity
epitope corresponding to amino acids 1-96 representing full length LSm8 of human origin
recommended for detection of LSm8 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine, porcine and avian:
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.