Application
Western blot analysis of MBLAC2 expression in non-transfected: (A) and human MBLAC2 transfected: (B) 293T whole cell lysates and mouse brain tissue extract (C).Application
Western blot analysis of MBLAC2 expression in mouse small intestine tissue extract.| Product Name | MBLAC2 Antibody (D-12) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope mapping near the N-terminus of MBLAC2 of human origin |
| Modification Notes | MBLAC2 (metallo-beta-lactamase domain-containing protein 2), also known as beta-lactamase-like, is a 279 amino acid protein that belongs to the glyoxalase II family and metallo-beta-lactamase superfamily. Existing as two alternatively spliced isoforms, MBLAC2 binds two zinc ions and is encoded by a gene that maps to human chromosome 5q14.3. Chromosome 5 contains 181 million base pairs and comprises nearly 6% of the human genome. Chromosome 5 is associated with Cockayne syndrome through the ERCC8 gene and familial adenomatous polyposis through the adenomatous polyposis coli (APC) tumor suppressor gene. Treacher Collins syndrome is also chromosome 5-associated and is caused by insertions or deletions within the TCOF1 gene. Deletion of the p arm of chromosome 5 leads to Cri du chat syndrome, while deletion of the q arm or of chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of MBLAC2 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping near the N-terminus of MBLAC2 of human origin |
|---|---|
| Tissue Specificity | epitope mapping near the N-terminus of MBLAC2 of human origin |
| Entrez Gene | 153364 |
|---|
Application
Western blot analysis of MBLAC2 expression in non-transfected: (A) and human MBLAC2 transfected: (B) 293T whole cell lysates and mouse brain tissue extract (C).
Application
Western blot analysis of MBLAC2 expression in mouse small intestine tissue extract.| Application Notes | recommended for detection of MBLAC2 of mouse, rat and human origin by WB, IP, IF and ELISA also reactive with additional species, including equine, canine, bovine and porcine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
