Application
Western blot analysis of NaDC-3 expression in Jurkat whole cell lysate.Application
Immunoperoxidase staining of formalin-fixed, paraffin-embedded human kidney tissue showing cytoplasmic localization.| Product Name | NaDC-3 Antibody (G-23) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | recommended for detection of NaDC-3 of human origin by WB, IP, IF, IHC(P) and ELISA |
| Modification Notes | NaDC-3 (Na(+)/dicarboxylate cotransporter 3), also known as SLC13A3 (solute carrier family 13 (sodium-dependent dicarboxylate transporter), member 3) or SDCT2 (sodium-dependent high-affinity dicarboxylate transporter 2), is a 602 amino acid multi-pass membrane protein and high-affinity sodium-dicarboxylate cotransporter that exists as four alternatively spliced isoforms. As a member of the solute carrier family 13 (SLC13) gene family, NaDC-3 couples the transport of sodium and Krebs cycle intermediates, including succinate and citrate, across the plasma membrane. NaDC-3 binds three sodium ions followed by a divalent anion substrate, which results in one positive charge across the membrane. The gene encoding human NaDC-3 is localized to chromosome 20 and is expressed in kidney, liver, placenta, brain and pancreas. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFIHCELISA |
| WB:1:500~1:2000 IP:1:100~1:500 IF:1:200~1:500 IHC:1:50~1:200 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | recommended for detection of NaDC-3 of human origin by WB IP IF IHC(P) and ELISA |
|---|---|
| Tissue Specificity | recommended for detection of NaDC-3 of human origin by WB, IP, IF, IHC(P) and ELISA |
| Entrez Gene | 64849 |
|---|
Application
Western blot analysis of NaDC-3 expression in Jurkat whole cell lysate.
Application
Immunoperoxidase staining of formalin-fixed, paraffin-embedded human kidney tissue showing cytoplasmic localization.| Application Notes | WB:1:500~1:2000 IP:1:100~1:500 IF:1:200~1:500 IHC:1:50~1:200 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
