Application
Western blot analysis of SERTAD2 expression in human fetal liver tissue extract.| Product Name | SERTAD2 Antibody (B-22) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | recommended for detection of SERTAD2 of mouse, rat and human origin by WB, IP and ELISA |
| Modification Notes | SERTAD2 (SERTA domain containing 2), also known as Sei-2 or TRIP-Br2, is a 314 amino acid protein that contains one SERTA domain and functions to integrate the signals provided by transcription factors at E2F-responsive promoters, thereby enhancing the effect of select transcription factors on DNA. Overexpression of SERTAD2 is thought to promote carcinogenesis, suggesting a role for SERTAD2 in tumor formation and metastasis. The gene encoding SERTAD2 maps to human chromosome 2, which houses over 1,400 genes and comprises nearly 8% of the human genome. Harlequin icthyosis, a rare and morbid skin deformity, is associated with mutations in the ABCA12 gene, while the lipid metabolic disorder sitosterolemia is associated with defects in the ABCG5 and ABCG8 genes. Additionally, an extremely rare recessive genetic disorder, Alström syndrome, is caused by mutations in the ALMS1 gene, which maps to chromosome 2. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPELISA |
| WB:1:500~1:2000 IP:1:100~1:500 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | recommended for detection of SERTAD2 of mouse rat and human origin by WB IP and ELISA |
|---|---|
| Tissue Specificity | recommended for detection of SERTAD2 of mouse, rat and human origin by WB, IP and ELISA |
| Entrez Gene | 9792 |
|---|
Application
Western blot analysis of SERTAD2 expression in human fetal liver tissue extract.| Application Notes | WB:1:500~1:2000 IP:1:100~1:500 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
