Application
Western blot analysis of γ-sarcoglycan expression in human fetal heart tissue extract.| Product Name | γ-sarcoglycan Antibody (Z-24) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | The sarcoglycan transmembrane proteins are members of the dystrophin complex. Sarcoglycans cluster together to form a complex, which is localized in the cell membrane of skeletal, cardiac, and smooth muscle fibers. Four sarcoglycan subunit proteins, designated å-, ∫-, ©- and ∂-sarcoglycan, form a complex on the skeletal muscle cell surface membrane. A genetic defect in any one of these proteins causes the loss or marked decrease of the whole sarcoglycan complex, which is observed in the autosomal recessive muscular dystrophy, sarcoglycanopathy. In smooth muscle, ∫- and ∂-sarcoglycans are associated with é-sarcoglycan, a glycoprotein homologous to å-sarcoglycan. Additionally, a complete deficiency in ∂-sarcoglycan is the cause of the Syrian hamster BIO.14 cardiomyopathy. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPELISA |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | recommended for detection of &gamma -sarcoglycan of mouse rat and human origin by WB IP and ELISA also reactive with additional species including canine |
|---|---|
| Tissue Specificity | recommended for detection of γ-sarcoglycan of mouse, rat and human origin by WB, IP and ELISA; also reactive with additional species, including canine |
| Entrez Gene | 6445 |
|---|
Application
Western blot analysis of γ-sarcoglycan expression in human fetal heart tissue extract.| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
