Application
Western blot analysis of human GDC transfected 293T whole cell lysate.| Product Name | GDC Antibody (L-24) |
|---|---|
| Antibody Type | Primary Antibodies |
| Modification Notes | GDC (Graves disease carrier protein), also known as SLC25A16 (solute carrier family 25 member 16), member 16), ML7, GDA or HGT.1, is a 332 amino acid multi-pass membrane protein belonging to the mitochondrial carrier family. Localizing to mitochondrial inner membrane, GDC is essential for the accumulation of coenzyme A in the mitochondrial matrix and facilitates the transport and exchange of molecules between the cytosol and the mitochondrial matrix space. GDC contains three Solcar repeats and is encoded by a gene mapping to human chromosome 10q21.3, a region associated with Graves disease. Making up 4.5% of the human genome, chromosome 10 encodes roughly 800 genes including PTEN, a tumor suppressor gene that has been linked to the development of Cowden syndrome. The chromosome 10 encoded gene ERCC6 is important for DNA repair and is linked to Cockayne syndrome which is characterized by extreme photosensitivity and premature aging. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPELISA |
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | recommended for detection of GDC of mouse rat and human origin by WB IP and ELISA |
|---|---|
| Tissue Specificity | recommended for detection of GDC of mouse, rat and human origin by WB, IP and ELISA |
| Entrez Gene | 8034 |
|---|
Application
Western blot analysis of human GDC transfected 293T whole cell lysate.| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
