| Product Name | FDX1L Antibody (C-13) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope mapping at the C-terminus of FDX1L of human origin |
| Modification Notes | Adrenodoxin (Adx) is an acidic [2Fe-2S] adrenal ferredoxin that belongs to the vertebrate ferredoxin family. ADX functions as a soluble electron carrier between the NADPH-dependent adrenodoxin reductase and cytochrome P450. ADX localizes to the adrenal cortex mitochondrial matrix, where it participates in the synthesis of Vitamin D and bile acids. FDX1L is an Adx-like protein that is encoded by a gene that maps to human chromosome 19, which consists of over 63 million bases, houses approximately 1,400 genes and is recognized for having the greatest gene density of the human chromosomes. It is the genetic home for a number of immunoglobulin (Ig) superfamily members, including the killer cell and leukocyte Ig-like receptors, a number of ICAMs, the CEACAM and PSG family and Fc receptors (FcRs). Key genes for eye color and hair color also map to chromosome 19. Peutz-Jeghers syndrome, spinocerebellar ataxia type 6, the stroke disorder CADASIL, hypercholesterolemia and insulin-dependent diabetes have been linked to chromosome 19. Translocations with chromosome 19 and chromosome 14 can be seen in some lymphoproliferative disorders and typically involve the proto-oncogene BCL3. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIFELISA |
| recommended for detection of FDX1L of mouse, rat and human origin by WB, IF and ELISA non cross-reactive with ADX or Fdx1 also reactive with additional species, including canine, bovine and porcine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping at the C-terminus of FDX1L of human origin |
|---|---|
| Tissue Specificity | epitope mapping at the C-terminus of FDX1L of human origin |
| Entrez Gene | 112812 |
|---|
| Application Notes | recommended for detection of FDX1L of mouse, rat and human origin by WB, IF and ELISA non cross-reactive with ADX or Fdx1 also reactive with additional species, including canine, bovine and porcine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
