epitope mapping within an internal region of C15orf40 of human origin
Modification Notes
Encoding more than 700 genes, chromosome 15 is made up of approximately 106 million base pairs and is about 3% of the human genome. Angelman and Prader-Willi syndromes are associated with loss of function or deletion of genes in the 15q11-q13 region. In the case of Angelman syndrome, this loss is due to inactivity of the maternal 15q11-q13 encoded UBE3A gene in the brain by either chromosomal deletion or mutation. In cases of Prader-Willi syndrome, there is a partial or complete deletion of this region from the paternal copy of chromosome 15. Tay-Sachs disease is a lethal disorder associated with mutations of the HEXA gene, which is encoded by chromosome 15. Marfan syndrome is associated with chromosome 15 through the FBN1 gene. The C15orf40 gene product has been provisionally designated C15orf40 pending further characterization.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIFELISA
recommended for detection of C15orf40 of human origin by WB, IF and ELISA non cross-reactive with other C15orf family members also reactive with additional species, including canine and porcine:
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
epitope mapping within an internal region of C15orf40 of human origin
Tissue Specificity
epitope mapping within an internal region of C15orf40 of human origin
Western blot analysis of C15orf40 expression in non-transfected: (A) and human C15orf40 transfected: (B) 293T whole cell lysates.
Application Notes
recommended for detection of C15orf40 of human origin by WB, IF and ELISA non cross-reactive with other C15orf family members also reactive with additional species, including canine and porcine:
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.