Application
Western blot analysis of NSUN6 expression in non-transfected: (A) and human NSUN6 transfected: (B) 293T whole cell lysates.Application
Western blot analysis of NSUN6 expression in human fetal muscle tissue extract.| Product Name | NSUN6 Antibody (T-24) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | recommended for detection of NSUN6 of mouse, rat and human origin by WB, IP and ELISA |
| Modification Notes | The nucleolus consists of a number of specific proteins that play a critical role in the assembly of ribosomes, as well as in the maintenance and structural integrity of the nucleolus. NSUN6 ( NOL1/NOP2/Sun domain family member 6), also known as NOPD1 (NOL1/NOP2/Sun and PUA domain-containing protein 1), is a 469 amino acid protein that belongs to the methyltransferase superfamily. NSUN6 contains 1 PUA domain and may have S-adenosyl-L-methionine-dependent methyl-transferase activity. The gene encoding NSUN6 maps to human chromosome 10, which houses over 1,200 genes and comprises nearly 4.5% of the human genome. Defects in some of the genes that map to chromosome 10 are associated with Charcot-Marie Tooth disease, Jackson-Weiss syndrome, Usher syndrome, nonsyndromatic deafness, Wolman’s syndrome, Cowden syndrome, multiple endocrine neoplasia type 2 and porphyria. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPELISA |
| WB:1:500~1:2000 IP:1:100~1:500 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | recommended for detection of NSUN6 of mouse rat and human origin by WB IP and ELISA |
|---|---|
| Tissue Specificity | recommended for detection of NSUN6 of mouse, rat and human origin by WB, IP and ELISA |
| Entrez Gene | 221078 |
|---|
Application
Western blot analysis of NSUN6 expression in non-transfected: (A) and human NSUN6 transfected: (B) 293T whole cell lysates.
Application
Western blot analysis of NSUN6 expression in human fetal muscle tissue extract.| Application Notes | WB:1:500~1:2000 IP:1:100~1:500 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
