| Modification Notes |
Olfactory receptors are G protein-coupled receptors that localize to the cilia of olfactory sensory neurons where they display affinity for and bind to a variety of odor molecules. The genes encoding olfactory receptors comprise the largest family in the human genome. The binding of olfactory receptor proteins to odor molecules triggers a signal transduction that propagates nerve impulses throughout the body, ultimately leading to transmission of the signal to the brain and the subsequent perception of smell. OR11H1 (olfactory receptor 11H1) is a 326 amino acid protein. The gene encoding OR11H1 maps to human chromosome 22. OR11H12 (olfactory receptor, family 11, subfamily H, member 12) is a 326 amino acid odorant receptor encoded by a gene located on human chromosome 14. |