Application
Western blot analysis of FOXF1 expression in human placenta tissue extract.| Product Name | FOXF1 Antibody (F-24) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | recommended for detection of FOXF1 of human origin by WB, IP and ELISA |
| Modification Notes | The FOX family of transcription factors share a common DIUA binding domain termed a winged-helix or forkhead domain. Many FOX proteins play important roles in development, metabolism, cancer and aging. Development of the vertebrate gut is controlled by paracrine crosstalk between the endodermal epithelium and the associated splanchnic mesoderm. FOXF1, previously designated HFH-8 or Freac-1, is expressed in the splanchnic mesoderm and required for proper development of gut-derived organs, including the liver, gallbladder, lung and intestinal tract. Inactivation of FOXF1 results in a range of defects, including megacolon, colorectal muscle hypoplasia and agangliosis. FOXF1 controls epithelial proliferation and survival and links hedgehog proteins to BMP and Wnt signaling pathways. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPELISA |
| WB:1:500~1:2000 IP:1:100~1:500 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | recommended for detection of FOXF1 of human origin by WB IP and ELISA |
|---|---|
| Tissue Specificity | recommended for detection of FOXF1 of human origin by WB, IP and ELISA |
| Entrez Gene | 2294 |
|---|
Application
Western blot analysis of FOXF1 expression in human placenta tissue extract.| Application Notes | WB:1:500~1:2000 IP:1:100~1:500 Notes:Optimal dilutions/concentrations should be determined by the researcher. |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
