Western blot analysis of UTY expression in non-transfected: (A) and mouse UTY transfected: (B) 293T whole cell lysates and HeLa (C) and MCF7 (D) nuclear extracts.
epitope mapping within an internal region of UTY of human origin
Modification Notes
Tup1 and Ssn6 are yeast proteins that, after being recruited to different promotor regions by DNA-binding proteins, form a transcription repressor complex that regulates gene expression. The Groucho/transducin-like Enhancer of split (TLE) family is the vertebrate ortholog of the Tup family and is functionally paired with the vertabrate Ssn6-like protein UTY. UTY is a product of the ubiquitously transcribed tetratricopeptide-repeat genes found on the Y chromosome. Interacting with TLE1 or TLE2, UTY acts to regulate the expression of particular genes. A related gene, found on the X chromosome, encodes the UTX protein that functions in a similar manner.
Key Feature
Clonality
Polyclonal
Isotype
IgG
Host Species
Rabbit
Tested Applications
WBIPIFELISA
recommended for detection of UTY of human origin by WB, IP, IF and ELISA:
Species Reactivity
HumanMouseRat
Concentration
1mg/ml
Purification
Affinity purified
Target Information
Alternative Names
epitope mapping within an internal region of UTY of human origin
Tissue Specificity
epitope mapping within an internal region of UTY of human origin
Western blot analysis of UTY expression in non-transfected: (A) and mouse UTY transfected: (B) 293T whole cell lysates and HeLa (C) and MCF7 (D) nuclear extracts.
Application Notes
recommended for detection of UTY of human origin by WB, IP, IF and ELISA:
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.