| Modification Notes |
CYorf15A (chromosome Y open reading frame 15A) is a 182 amino acid protein that is ubiquitously expressed and is encoded by a gene which maps to human chromosome Y. Chromosome Y contains approximately 58 million base pairs and houses over 80 genes, many of which are essential for proper sexual development. The Y chromosome is the human sex determining chromosome, necessary for male development and, while deletions or defects in chromosome Y-encoded genes are not lethal, they may greatly impair masculine development and function. Carrying an additional copy of the Y chromosome, as seen in males with XYY Syndrome, does not lead to an obvious phenotype and most XYY males are unaware of their additional Y chromosome. |