| Modification Notes |
LOC643001 is a 110 amino acid protein that is encoded by a gene which maps to human chromosome Y. Chromosome Y contains approximately 58 million base pairs and houses over 80 genes, many of which are essential for proper sexual development. The Y chromosome is the human sex determining chromosome, necessary for male development. While deletions or defects in chromosome Y-encoded genes are not lethal, they may greatly impair masculine development and function. Carrying an additional copy of the Y chromosome, as seen in males with XYY syndrome, does not lead to an obvious phenotype and most XYY males are unaware of their additional Y chromosome. The LOC643001 gene product has been provisionally designated LOC643001 pending further characterization. |