Application
Western blot analysis of NNP-1 expression in HeLa nuclear extract.| Product Name | NNP-1 Antibody (A-14) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope mapping within an internal region of NNP-1 of human origin |
| Modification Notes | Novel nuclear protein 1 (NNP-1), also known as RRP1-like protein or Nucleolar protein Nop52, is a 461 amino acid protein belonging to the RRP1 family. Localized to the nucleolus, NNP-1 has simian virus 40-type and bipartite nuclear localization signals and four coiled-coil domains within its C-terminal region. NNP-1 has been found to play an important role in the generation of 28S rRNA in the late processing steps of ribosome biogenesis. At the end of mitosis, nucleolar proteins assemble in a sequential order during the rebuilding of the nucleolus. NNP-1 assembles after Fibrillarin and C23, and simultaneously with B23 and POP1 in the prenucleolar body pathway. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFELISA |
| recommended for detection of NNP-1 of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with other RRP family members also reactive with additional species, including bovine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope mapping within an internal region of NNP-1 of human origin |
|---|---|
| Tissue Specificity | epitope mapping within an internal region of NNP-1 of human origin |
| Entrez Gene | 8568 |
|---|
Application
Western blot analysis of NNP-1 expression in HeLa nuclear extract.| Application Notes | recommended for detection of NNP-1 of mouse, rat and human origin by WB, IP, IF and ELISA non cross-reactive with other RRP family members also reactive with additional species, including bovine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
