| Product Name | FMNL1 Antibody (H-60) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | epitope corresponding to amino acids 161-220 mapping within an internal region of FMNL1 of human origin |
| Modification Notes | Formin-like protein 1 (FMNL1, formin-related protein, Frl) is a 1,094 amino acid protein encoded by the mouse gene Fmnl1. FMNL1 belongs to the formin homology family and has one DAD (diaphanous autoregulatory domain), one FH2 (formin homology 2) domain, and one GBD/FH3 (Rho GTPase-binding/formin homology 3) domain. Formins are a conserved class of proteins expressed in all eukaryotes, with known roles in generating cellular Actin-based structures. FMNL1 is believed to play a role in the control of cell motility and survival of macrophages. FMNL1 has been found to interact with Rac 1, PFN1 and PFN2 and can block apoptotic cell death and inhibit cell adhesion and migration. FMNL1 is located in the cytoplasm and is highly expressed in the spleen, lymph nodes and bone marrow cells. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIFELISA |
| recommended for detection of FMNL1, also designated Formin-like protein 1, of mouse, rat and human origin by WB, IF and ELISA also reactive with additional species, including equine, canine and porcine: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | epitope corresponding to amino acids 161-220 mapping within an internal region of FMNL1 of human origin |
|---|---|
| Tissue Specificity | epitope corresponding to amino acids 161-220 mapping within an internal region of FMNL1 of human origin |
| Entrez Gene | 752 |
|---|
| Application Notes | recommended for detection of FMNL1, also designated Formin-like protein 1, of mouse, rat and human origin by WB, IF and ELISA also reactive with additional species, including equine, canine and porcine: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
