Application
Western blot analysis of PFKP expression in non-transfected 293T: (A), human PFKP transfected 293T: (B) and Jurkat (C) whole cell lysates.Application
Western blot analysis of PFKP expression in HeLa whole cell lysate.Application
Western blot analysis of PFKP expression in non-transfected: (A) and human PFKP transfected: (B) 293T whole cell lysates.Application
Western blot analysis of PFKP expression in Ramos whole cell lysate.Application
Immunoperoxidase staining of formalin fixed, paraffin-embedded human cancer tissue showing cytoplasmic staining.| Product Name | PFKP Antibody (C-23) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | recommended for detection of PFKP of human origin by WB, IP, IF, IHC(P) and ELISA |
| Modification Notes | Phosphofructokinases (PFKs) are regulatory glycolytic enzymes which catalyze the irreversible conversion of fructose-6-phosphate to fructose-1,6-bisphosphate, an intermediate in the pathway of glycolysis. Mammalian PFK is a tetramer made of three subunits, namely muscle (PFK-1), liver (PFKL) and platelet (PFKP) phosphofructokinase. PFKP (phosphofructokinase, platelet), also known as PFKF or PFK-C, is a 784 amino acid subunit of the PFK complex. Using magnesium as a cofactor, PFKP functions as an allosteric enzyme that, together with other PFK subunits, catalyzes the ATP-dependent phosphorylation of fructose-6-phosphate. Defects in the gene encoding PFKP may lead to an increased risk of obesity, as PFKP plays a crucial role in carbohydrate metabolism. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIPIFIHCELISA |
| See 1 citations for PFKPAntibody (C-23): |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | recommended for detection of PFKP of human origin by WB IP IF IHC(P) and ELISA |
|---|---|
| Tissue Specificity | recommended for detection of PFKP of human origin by WB, IP, IF, IHC(P) and ELISA |
| Entrez Gene | 5214 |
|---|
Application
Western blot analysis of PFKP expression in non-transfected 293T: (A), human PFKP transfected 293T: (B) and Jurkat (C) whole cell lysates.
Application
Western blot analysis of PFKP expression in HeLa whole cell lysate.
Application
Western blot analysis of PFKP expression in non-transfected: (A) and human PFKP transfected: (B) 293T whole cell lysates.
Application
Western blot analysis of PFKP expression in Ramos whole cell lysate.
Application
Immunoperoxidase staining of formalin fixed, paraffin-embedded human cancer tissue showing cytoplasmic staining.| Application Notes | See 1 citations for PFKPAntibody (C-23): |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
