Application
Western blot analysis of BRD8 expression in non-transfected: (A) and mouse BRD8 transfected: (B) 293T whole cell lysates.Application
Western blot analysis of BRD8 expression in mouse skeletal muscle tissue extract.| Product Name | BRD8 Antibody (H-15) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | raised against BRD8 of human origin |
| Modification Notes | BRD8 (bromodomain containing protein 8), also designated Skeletal muscle abundant protein (SMAP or SMAP2) or Thyroid hormone receptor coactivating protein 120kDa (p120 or TrCP120), is a 1235 amino acid transcription regulation factor that contains two bromodomains and is expressed in adipose tissue, brain, heart, kidney, liver, lung, pancreas, placenta and skeletal muscle. BRD8 mRNA is upregulated during neointima formation in a rat carotid endarterectomy model and may therefore be involved in the progression of atherosclerosis in aorta. BRD8 is a member of the NuA4 histone acetyltransferase complex, which may be responsible for the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, apoptosis and DNA repair. |
| Clonality | Polyclonal |
|---|---|
| Isotype | IgG |
| Host Species | Rabbit |
| Tested Applications | WBIP |
| recommended for detection of BRD8 of mouse and human origin by WB and IP: |
|
| Species Reactivity | HumanMouseRat |
| Concentration | 1mg/ml |
| Purification | Affinity purified |
| Alternative Names | raised against BRD8 of human origin |
|---|---|
| Tissue Specificity | raised against BRD8 of human origin |
| Entrez Gene | 10902 |
|---|
Application
Western blot analysis of BRD8 expression in non-transfected: (A) and mouse BRD8 transfected: (B) 293T whole cell lysates.
Application
Western blot analysis of BRD8 expression in mouse skeletal muscle tissue extract.| Application Notes | recommended for detection of BRD8 of mouse and human origin by WB and IP: |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
